Associations of testosterone and sex hormone binding globulin with adipose tissue hormones in midlife women.

ABSTRACT:

Objective

Regulators of adipose tissue hormones remain incompletely understood, but may include sex hormones. As adipose tissue hormones have been shown to contribute to numerous metabolic and cardiovascular disorders, understanding their regulation in midlife women is of clinical importance. Therefore, we assessed the associations between testosterone (T) and sex hormone binding globulin (SHBG) with leptin, high molecular weight (HMW) adiponectin, and the soluble form of the leptin receptor (sOB-R) in healthy midlife women.

Design and methods

Cross-sectional analyses were performed using data from 1,881 midlife women (average age 52.6 (±2.7) years) attending the sixth Annual follow-up visit of the multiethnic Study of Women's Health Across the Nation.

Results

T was w

SUBMITTER: Wildman RP 

PROVIDER: S-EPMC4109046 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature