Gene-diet interactions in gastric cancer risk: a systematic review.

ABSTRACT:

Aim

To conduct a systematic review of the published epidemiological studies investigating the association of the interactions between gene variants and dietary intake with gastric cancer risk.

Methods

A literature search was conducted in PubMed, EMBASE, and MEDLINE for articles published between January 2000 and July 2013, and 38 studies were identified. Previous studies included various dietary factors (e.g., fruits and vegetables, soybean products, salt, meat, and alcohol) and genetic variants that are involved in various metabolic pathways.

Results

Studies suggest that individuals who carry high-risk genetic variants and demonstrate particular dietary habits may have an increased risk of gastric cancer compared with those who do not carry high-risk genetic variants

SUBMITTER: Kim J 

PROVIDER: S-EPMC4110595 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature