Reducing dietary loading decreases mouse temporomandibular joint degradation induced by anterior crossbite prosthesis.

ABSTRACT:

Objective

Dietary loading has been reported to have an effect on temporomandibular joint (TMJ) remodeling via periodontal-muscular reflex. We therefore examined whether reducing dietary loading decreased TMJ degradation induced by the unilateral anterior crossbite prosthesis as we recently reported.

Methods

Forty 6-week-old female C57BL/6J mice were randomly divided into two experimental and two control groups. One experimental and one control group received small-size diet and the other two groups received large-size diet. Unilateral anterior crossbite prosthesis was created in the two experimental groups. The TMJ samples were collected 3 weeks after experimental operation. Histological changes in condylar cartilage and subchondral bone were assessed by Hematoxylin & Eosin,

SUBMITTER: Liu YD 

PROVIDER: S-EPMC4111231 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature