Predictors of disease progression in pediatric dilated cardiomyopathy.

ABSTRACT:

Background

Despite medical advances, children with dilated cardiomyopathy (DCM) remain at high risk of death or need for cardiac transplantation. We sought to identify predictors of disease progression in pediatric DCM.

Methods and results

The Pediatric Heart Network evaluated chronic DCM patients with prospective echocardiographic and clinical data collection during an 18-month follow-up. Inclusion criteria were age <22 years and DCM disease duration >2 months. Patients requiring intravenous inotropic/mechanical support or listed status 1A/1B for transplant were excluded. Disease progression was defined as an increase in transplant listing status, hospitalization for heart failure, intravenous inotropes, mechanical support, or death. Predictors of disease progression were i

SUBMITTER: Molina KM 

PROVIDER: S-EPMC4111626 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature