Long-term overall and disease-specific mortality associated with benign gynecologic surgery performed at different ages.

ABSTRACT:

Objective

As bilateral salpingo-oophorectomy is frequently performed with hysterectomy for nonmalignant conditions, defining health outcomes associated with benign bilateral salpingo-oophorectomy performed at different ages is critical.

Methods

We assessed mortality risk associated with benign total abdominal hysterectomy or bilateral salpingo-oophorectomy among 52,846 Breast Cancer Detection Demonstration Project follow-up study participants. Surgery and risk factor data were ascertained via baseline interview (1979-1986) and three questionnaires (1987-1998). During follow-up through December 2005 (mean, 22.1 y), 13,734 deaths were identified. We estimated hazard ratios (HRs) and 95% CIs for overall and disease-specific mortality for total abdominal hysterectomy or bilatera

SUBMITTER: Gierach GL 

PROVIDER: S-EPMC4113222 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature