Performance of creatinine-based GFR estimating equations in solid-organ transplant recipients.

ABSTRACT:

Background

Accurate assessment of kidney function is important for the management of solid-organ transplant recipients. In other clinical populations, glomerular filtration rate (GFR) most commonly is estimated using the CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration) creatinine or the 4-variable MDRD (Modification of Diet in Renal Disease) Study equation. The accuracy of these equations compared with other GFR estimating equations in transplant recipients has not been carefully studied.

Study design

Diagnostic test study.

Setting & participants

Solid-organ transplant recipients longer than 6 months posttransplantation from 5 clinical populations (N=3,622, including recipients of kidney [53%], liver [35%], and other or multiple organs [12%]).

Index test

SUBMITTER: Shaffi K 

PROVIDER: S-EPMC4113340 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature