Sexual function in women on estradiol or venlafaxine for hot flushes: a randomized controlled trial.

ABSTRACT:

Objective

To evaluate sexual function in midlife women taking low-dose oral estradiol or venlafaxine for hot flushes.

Methods

In an 8-week randomized controlled trial among women aged 40-62 years, sexual function was compared between 0.5 mg oral estradiol per day or 75 mg venlafaxine per day (both compared with a placebo). Measures included composite and six domain scores from the Female Sexual Function Index and sexually related personal distress.

Results

Participants were aged 54.6 years (standard deviation [SD] 3.8) years, 59% white, with 8.1 (SD 5.3) daily hot flushes. Median composite baseline Female Sexual Function Index score was 16.3 (SD 11.9, n=256) for all women and 21.7 (SD 9.3, n=198) among sexually active women. Composite mean Female Sexual Function Index

SUBMITTER: Reed SD 

PROVIDER: S-EPMC4113909 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature