4D reconstruction of the beating embryonic heart from two orthogonal sets of parallel optical coherence tomography slice-sequences.

ABSTRACT: Current methods to build dynamic optical coherence tomography (OCT) volumes of the beating embryonic heart involve synchronization of 2D+time slice-sequences acquired over separate heartbeats. Temporal registration of these sequences is performed either through gating or postprocessing. While synchronization algorithms that exclusively rely on image- intrinsic signals allow forgoing external gating hardware, they are prone to error accumulation, require operator-supervised correction, or lead to nonisotropic resolution. Here, we propose an image-based, retrospective reconstruction technique that uses two sets of parallel 2D+T slice-sequences, acquired perpendicularly to each other, to yield accurate and automatic reconstructions with isotropic resolution. The method utilizes the similarity

SUBMITTER: Bhat S 

PROVIDER: S-EPMC4114225 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature