Reduced brain resting-state network specificity in infants compared with adults.

ABSTRACT:

Purpose

Infant resting-state networks do not exhibit the same connectivity patterns as those of young children and adults. Current theories of brain development emphasize developmental progression in regional and network specialization. We compared infant and adult functional connectivity, predicting that infants would exhibit less regional specificity and greater internetwork communication compared with adults.

Patients and methods

Functional magnetic resonance imaging at rest was acquired in 12 healthy, term infants and 17 adults. Resting-state networks were extracted, using independent components analysis, and the resulting components were then compared between the adult and infant groups.

Results

Adults exhibited stronger connectivity in the posterior cingulate co

SUBMITTER: Wylie KP 

PROVIDER: S-EPMC4114919 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature