Analysis of sampling artifacts on the Granger causality analysis for topology extraction of neuronal dynamics.

ABSTRACT: Granger causality (GC) is a powerful method for causal inference for time series. In general, the GC value is computed using discrete time series sampled from continuous-time processes with a certain sampling interval length τ, i.e., the GC value is a function of τ. Using the GC analysis for the topology extraction of the simplest integrate-and-fire neuronal network of two neurons, we discuss behaviors of the GC value as a function of τ, which exhibits (i) oscillations, often vanishing at certain finite sampling interval lengths, (ii) the GC vanishes linearly as one uses finer and finer sampling. We show that these sampling effects can occur in both linear and non-linear dynamics: the GC value may vanish in the presence of true causal influence or become non-zero in the absence of causal i

SUBMITTER: Zhou D 

PROVIDER: S-EPMC4115622 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature