Leisure-time physical activity and all-cause mortality in an elderly cohort.

ABSTRACT:

Background

Physical activity is one of the mainstays of secondary prevention in people with heart disease. It is not well understood, however, how the presence of heart disease or a history of habitual exercise prior to the study modify any mortality-sparing effects of leisure-time physical activity.

Methods

We analyzed data from a well-described cohort of subjects aged 54 years and older at intake (median age, 70 years) from Sonoma, CA, studied between 1993 and 2001 with mortality follow-up until 2003. A history-adjusted marginal structural model was used to obtain counterfactual excess risk estimates that were pooled across the different time points. Additive interaction was examined by comparing these excess risk estimates across strata of age, heart disease, and precohor

SUBMITTER: Bembom O 

PROVIDER: S-EPMC4116188 | biostudies-literature | 2009 May

REPOSITORIES: biostudies-literature