Early coronary angiography and induced hypothermia are associated with survival and functional recovery after out-of-hospital cardiac arrest.

ABSTRACT:

Background

The rate and effect of coronary interventions and induced hypothermia after out-of-hospital cardiac arrest (OHCA) are unknown. We measured the association of early (≤24h after arrival) coronary angiography, reperfusion, and induced hypothermia with favorable outcome after OHCA.

Methods

We performed a secondary analysis of a multicenter clinical trial (NCT00394706) conducted between 2007 and 2009 in 10 North American regions. Subjects were adults (≥18 years) hospitalized after OHCA with pulses sustained ≥60min. We measured the association of early coronary catheterization, percutaneous coronary intervention, fibrinolysis, and induced hypothermia with survival to hospital discharge with favorable functional status (modified Rankin Score≤3).

Results

From 16,87

SUBMITTER: Callaway CW 

PROVIDER: S-EPMC4117649 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature