Parkinson's disease and REM sleep behavior disorder result in increased non-motor symptoms.

ABSTRACT:

Objective

Rapid eye movement (REM)-sleep behavior disorder (RBD) is often comorbid with Parkinson's disease (PD). The current study aimed to provide a detailed understanding of the impact of having RBD on multiple non-motor symptoms (NMS) in patients with PD.

Methods

A total of 86 participants were evaluated for RBD and assessed for multiple NMS of PD. Principal component analysis was utilized to model multiple measures of NMS in PD, and a multivariate analysis of variance was used to assess the relationship between RBD and the multiple NMS measures. Seven NMS measures were assessed: cognition, quality of life, fatigue, sleepiness, overall sleep, mood, and overall NMS of PD.

Results

Among the PD patients, 36 were classified as having RBD (objective polysomnography and

SUBMITTER: Neikrug AB 

PROVIDER: S-EPMC4117926 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature