MDSCs: the final frontier of the microenvironment in CLL?

ABSTRACT: In this issue of Blood, Jitschin et al identify increased numbers of myeloid-derived suppressor cells (MDSCs) in untreated patients with chronic lymphocytic leukemia (CLL) suppressing T cells and inducing regulatory T cells (T(regs)), resulting in impaired immune responses.

SUBMITTER: Zirlik K 

PROVIDER: S-EPMC4118477 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature