Intensive care unit admission in multiple sclerosis: increased incidence and increased mortality.

ABSTRACT:

Objective

To compare the incidence of, and mortality after, intensive care unit (ICU) admission as well as the characteristics of critical illness in the multiple sclerosis (MS) population vs the general population.

Methods

We used population-based administrative data from the Canadian province of Manitoba for the period 1984 to 2010 and clinical data from 93% of admissions to provincial high-intensity adult ICUs. We identified 5,035 prevalent cases of MS and a cohort from the general population matched 5:1 on age, sex, and region of residence. We compared these populations using incidence rates and multivariable regression models adjusting for age, sex, comorbidity, and socioeconomic status.

Results

From January 2000 to October 2009, the age- and sex-standardized ann

SUBMITTER: Marrie RA 

PROVIDER: S-EPMC4118502 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature