Single-base-resolution methylomes of Populus trichocarpa reveal the association between DNA methylation and drought stress.

ABSTRACT:

Background

DNA methylation is an important biological form of epigenetic modification, playing key roles in plant development and environmental responses.

Results

In this study, we examined single-base resolution methylomes of Populus under control and drought stress conditions using high-throughput bisulfite sequencing for the first time. Our data showed methylation levels of methylated cytosines, upstream 2 kp, downstream 2kb, and repeatitive sequences significantly increased after drought treatment in Populus. Interestingly, methylation in 100 bp upstream of the transcriptional start site (TSS) repressed gene expression, while methylations in 100-2000 bp upstream of TSS and within the gene body were positively associated with gene expression. Integrated with the transcrip

SUBMITTER: Liang D 

PROVIDER: S-EPMC4118614 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature