Processing speed and neurodevelopment in adolescent-onset psychosis: cognitive slowing predicts social function.

ABSTRACT: Onset of psychosis may be associated with abnormal adolescent neurodevelopment. Here we examined the neurocognitive profile of first-episode, adolescent onset psychosis (AOP) as compared to typically developing adolescents, and asked whether neurocognitive performance varied differentially as a function of age in the cases compared with controls. A comprehensive neuropsychological battery was administered to 35 patients experiencing a first-episode of a DSM-IV psychotic disorder and to 31 matched controls. Clinicians also rated subjects' social and role functioning, both at the time of neuropsychological assessment and 1 year later. Although patients displayed a wide range of impairments relative to controls, their most pronounced deficits included verbal memory, sensorimotor dexterity and

SUBMITTER: Bachman P 

PROVIDER: S-EPMC4119229 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature