Differences in the expression of chromosome 1 genes between lung telocytes and other cells: mesenchymal stem cells, fibroblasts, alveolar type II cells, airway epithelial cells and lymphocytes.

ABSTRACT: Telocytes (TCs) are a unique type of interstitial cells with specific, extremely long prolongations named telopodes (Tps). Our previous study showed that TCs are distinct from fibroblasts (Fbs) and mesenchymal stem cells (MSCs) as concerns gene expression and proteomics. The present study explores patterns of mouse TC-specific gene profiles on chromosome 1. We investigated the network of main genes and the potential functional correlations. We compared gene expression profiles of mouse pulmonary TCs, MSCs, Fbs, alveolar type II cells (ATII), airway basal cells (ABCs), proximal airway cells (PACs), CD8(+) T cells from bronchial lymph nodes (T-BL) and CD8(+) T cells from lungs (T-LL). The functional and feature networks were identified and compared by bioinformatics tools. Our data showed th

SUBMITTER: Sun X 

PROVIDER: S-EPMC4119386 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature