Gold-catalyzed diastereoselective cycloisomerization of alkylidene-cyclopropane-bearing 1,6-diynes.

ABSTRACT: An unprecedented gold-catalyzed diastereoselective cycloisomerization of 1,6-diynes bearing an alkylidene cyclopropane moiety has been developed. This methodology enables rapid access to a variety of 1,2-trimethylenenorbornanes, which are important building blocks in the preparations of abiotic and sesquiterpene core structures.

SUBMITTER: Zheng H 

PROVIDER: S-EPMC4120096 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature