Drug treatment of macular oedema secondary to central retinal vein occlusion: a network meta-analysis.

ABSTRACT:

Objective

To indirectly compare aflibercept, bevacizumab, dexamethasone, ranibizumab and triamcinolone for treatment of macular oedema secondary to central retinal vein occlusion using a network meta-analysis (NMA).

Design nma data sources

The following databases were searched from January 2005 to March 2013: MEDLINE, MEDLINE In-process, EMBASE; CDSR, DARE, HTA, NHSEED, CENTRAL; Science Citation Index and Conference Proceedings Citation Index-Science.

Eligibility criteria for selecting studies

Only randomised controlled trials assessing patients with macular oedema secondary to central retinal vein occlusion were included. Studies had to report either proportions of patients gaining ≥3 lines, losing ≥3 lines, or the mean change in best corrected visual acuity. Two aut

SUBMITTER: Ford JA 

PROVIDER: S-EPMC4120318 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature