Blood pressure trajectories in early adulthood and subclinical atherosclerosis in middle age.

ABSTRACT:

Importance

Single measures of blood pressure (BP) levels are associated with the development of atherosclerosis; however, long-term patterns in BP and their effect on cardiovascular disease risk are poorly characterized.

Objectives

To identify common BP trajectories throughout early adulthood and to determine their association with presence of coronary artery calcification (CAC) during middle age.

Design, setting, and participants

Prospective cohort data from 4681 participants in the CARDIA study, who were black and white men and women aged 18 to 30 years at baseline in 1985-1986 at 4 urban US sites, collected through 25 years of follow-up (2010-2011). We examined systolic BP, diastolic BP, and mid-BP (calculated as [SBP+DBP]/2, an important marker of coronary heart d

SUBMITTER: Allen NB 

PROVIDER: S-EPMC4122296 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature