Vasodilators, blood pressure-lowering medications, and age-related macular degeneration: the Beaver Dam Eye Study.

ABSTRACT:

Objective

To examine the association of vasodilator and antihypertensive medication use with the incidence of age-related macular degeneration (AMD).

Design

Longitudinal population-based study.

Participants

Persons 43 to 86 years of age living in Beaver Dam, Wisconsin, from 1988 through 1990.

Methods

Examinations were performed every 5 years over a 20-year period. There were 9676 total person-visits over the course of the study. Status of AMD was determined from grading retinal photographs.

Main outcome measures

Incidence of AMD.

Results

The 5-year incidence of early AMD over the 20-year period was 8.4%; for late AMD, it was 1.4%; for pure geographic atrophy (GA), it was 0.6%; for exudative AMD, it was 0.9%; and for progression of AMD, it was 24.9

SUBMITTER: Klein R 

PROVIDER: S-EPMC4122609 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature