Clarifying the neural basis for incentive salience of tobacco cues in smokers.

ABSTRACT: In functional magnetic resonance imaging (fMRI) studies, smoking cues have been found to elicit increases in brain activity in regions associated with processing rewarding and emotional stimuli. However, most smoking cue studies to date have reported effects relative to neutral control stimuli with no incentive properties, making it unclear whether the observed activation pertains to value in general or the value of cigarettes in particular. The current fMRI study sought to clarify the neural activity reflecting tobacco-specific incentive value versus domain-general incentive value by examining smoking cues, neutral cues, and a third set of cues, monetary cues, which served as an active control condition. Participants were 42 male daily smokers. Compared to neutral cues, significantly grea

SUBMITTER: Gray JC 

PROVIDER: S-EPMC4125499 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature