Genome-wide association study of smoking behaviours among Bangladeshi adults.

ABSTRACT:

Background

The high prevalence of tobacco use in some developing nations, including Bangladesh, poses several public health challenges for these populations. Smoking behaviour is determined by genetic and environmental factors; however, the genetic determinants of smoking behaviour have not been previously examined in a Bangladeshi or South Asian population. We performed a genome-wide association study (GWAS) of tobacco smoking behaviour among a population-based sample of 5354 (2035 ever smokers and 3319 never smokers) men and women in Bangladesh.

Methods

Genome-wide association analyses were conducted for smoking initiation (ever vs never smokers), smoking quantity (cigarettes per day), age of smoking initiation, and smoking cessation (former vs current smokers). Sex-strati

SUBMITTER: Argos M 

PROVIDER: S-EPMC4126189 | biostudies-literature | 2014 May

REPOSITORIES: biostudies-literature