Copper-catalyzed regioselective ortho C-H cyanation of vinylarenes.

ABSTRACT: A copper-based catalytic technique for the regioselective ortho C-H cyanation of vinylarenes has been developed. This method provides an effective means for the selective functionalization of vinylarene derivatives. A copper-catalyzed cyanative dearomatization mechanism is proposed to account for the regiochemical course of this reaction.

SUBMITTER: Yang Y 

PROVIDER: S-EPMC4127133 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature