Depression and all-cause mortality in hemodialysis patients.

ABSTRACT:

Background

There are limited data regarding the relationship between depression and mortality in hemodialysis (HD) patients.

Methods

Among 323 patients receiving maintenance HD, depression symptoms were assessed using the Center for Epidemiologic Studies Depression (CES-D) scale, with a score of ≥16 consistent with depression. Adjusted Cox proportional-hazards models with additional analyses incorporating antidepressant medication use were used to evaluate the association between depression and mortality. Baseline CES-D scores were used for the primary analyses, while secondary time-dependent analyses incorporated subsequent CES-D results.

Results

The mean age was 62.9 ± 16.5 years, 46% of the subjects were women and 22% were African-American. The mean baseline CES-D

SUBMITTER: Fan L 

PROVIDER: S-EPMC4128686 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature