Urinary bacteria in adult women with urgency urinary incontinence.

ABSTRACT:

Introduction and hypothesis

This study's aims were to detect and quantify bacterial DNA in the urine of randomized trial participants about to undergo treatment for urinary urgency incontinence (UUI) without clinical evidence of urinary tract infection (UTI) and to determine if the presence of bacterial DNA in baseline urine relates to either baseline urinary symptoms or UTI risk after urinary tract instrumentation.

Methods

Women without clinical evidence of baseline UTI were randomized to cystoscopic onabotulinum toxin A injection and oral placebo medication versus cystoscopic placebo injection and active oral medication. Bacterial DNA in participants' catheterized urine was measured by quantitative polymerase chain reaction (qPCR).

Results

Bacterial DNA was detected

SUBMITTER: Brubaker L 

PROVIDER: S-EPMC4128900 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature