Ontology highlight
ABSTRACT:
SUBMITTER: Nakayasu ES
PROVIDER: S-EPMC4131070 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
International journal of proteomics 20140720
Lysine acetylation is a common protein posttranslational modification that regulates a variety of biological processes. A major bottleneck to fully understanding the functional aspects of lysine acetylation is the difficulty in measuring the proportion of lysine residues that are acetylated. Here we describe a mass spectrometry method using a combination of isotope labeling and detection of a diagnostic fragment ion to determine the stoichiometry of protein lysine acetylation. Using this techniq ...[more]