Comprehensive analysis of published studies involving systemic treatment for chondrosarcoma of bone between 2000 and 2013.

ABSTRACT:

Background

The majority of patients with chondrosarcoma of bone have an excellent overall survival after local therapy. However, in case of unresectable locally advanced or metastatic disease the outcome is poor and limited treatment options exist. Therefore we conducted a survey of clinical phase I or II trials and retrospective studies that described systemic therapy for chondrosarcoma patients.

Materials and methods

Using PubMed, clinicaltrials.gov, the Cochrane controlled trial register and American Society of Clinical Oncology (ASCO) abstracts a literature survey was conducted. From the identified items, data were collected by a systematic analysis. We limited our search to semi-recent studies published between 2000 and 2013 to include modern drugs, imaging techniques a

SUBMITTER: van Maldegem AM 

PROVIDER: S-EPMC4131227 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature