Predicting hematoma expansion after primary intracerebral hemorrhage.

ABSTRACT:

Importance

Many clinical trials focus on restricting hematoma expansion following acute intracerebral hemorrhage (ICH), but selecting those patients at highest risk of hematoma expansion is challenging.

Objective

To develop a prediction score for hematoma expansion in patients with primary ICH.

Design, setting, and participants

Prospective cohort study at 2 urban academic medical centers among patients having primary ICH with available baseline and follow-up computed tomography for volumetric analysis (817 patients in the development cohort and 195 patients in the independent validation cohort).

Main outcomes and measures

Hematoma expansion was assessed using semiautomated software and was defined as more than 6 mL or 33% growth. Covariates were tested for asso

SUBMITTER: Brouwers HB 

PROVIDER: S-EPMC4131760 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature