Sma3s: a three-step modular annotator for large sequence datasets.

ABSTRACT: Automatic sequence annotation is an essential component of modern 'omics' studies, which aim to extract information from large collections of sequence data. Most existing tools use sequence homology to establish evolutionary relationships and assign putative functions to sequences. However, it can be difficult to define a similarity threshold that achieves sufficient coverage without sacrificing annotation quality. Defining the correct configuration is critical and can be challenging for non-specialist users. Thus, the development of robust automatic annotation techniques that generate high-quality annotations without needing expert knowledge would be very valuable for the research community. We present Sma3s, a tool for automatically annotating very large collections of biological sequenc

SUBMITTER: Munoz-Merida A 

PROVIDER: S-EPMC4131829 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature