Modified treatment approach using cardiovascular disease risk calculator for primary prevention.

ABSTRACT:

Background

The recent guidelines for preventing atherosclerotic cardiovascular events are an important advancement. For primary prevention, statins are recommended if the ten-year risk is ≥ 5% (consideration for therapy) or ≥ 7.5% (definitive treatment unless contraindication after discussion). We rationalized that a significant cohort with ten-year risk below the treatment thresholds would predictably surpass them within the recommended 4-6 year window for reassessing the ten-year risk. As atherosclerosis is a progressive disease, these individuals may therefore benefit with more aggressive therapies even at baseline.

Methods and findings

We used publicly available NHANES dataset for ten-year risk calculation. There were 1805 participants. To evaluate the ten-year risk chan

SUBMITTER: Gupta H 

PROVIDER: S-EPMC4131882 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature