Bactericidal activities of GM flax seedcake extract on pathogenic bacteria clinical strains.

ABSTRACT:

Background

The antibiotic resistance of pathogenic microorganisms is a worldwide problem. Each year several million people across the world acquire infections with bacteria that are antibiotic-resistant, which is costly in terms of human health. New antibiotics are extremely needed to overcome the current resistance problem.

Results

Transgenic flax plants overproducing compounds from phenylpropanoid pathway accumulate phenolic derivatives of potential antioxidative, and thus, antimicrobial activity. Alkali hydrolyzed seedcake extract containing coumaric acid, ferulic acid, caffeic acid, and lignan in high quantities was used as an assayed against pathogenic bacteria (commonly used model organisms and clinical strains). It was shown that the extract components had antibacteri

SUBMITTER: Zuk M 

PROVIDER: S-EPMC4134466 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature