Accuracy of prediction equations for serum osmolarity in frail older people with and without diabetes.

ABSTRACT:

Background

Serum osmolality is an accurate indicator of hydration status in older adults. Glucose, urea, and electrolyte concentrations are used to calculate serum osmolarity, which is an indirect estimate of serum osmolality, but which serum osmolarity equations best predict serum osmolality in the elderly is unclear.

Objective

We assessed the agreement of measured serum osmolality with calculated serum osmolarity equations in older people.

Design

Serum osmolality was measured by using freezing point depression in a cross-sectional study. Plasma glucose, urea, and electrolytes were analyzed and entered into 38 serum osmolarity-prediction equations. The Bland-Altman method was used to evaluate the agreement and differential bias between measured osmolality and calcula

SUBMITTER: Siervo M 

PROVIDER: S-EPMC4135495 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature