VeA is associated with the response to oxidative stress in the aflatoxin producer Aspergillus flavus.

ABSTRACT: Survival of fungal species depends on the ability of these organisms to respond to environmental stresses. Osmotic stress or high levels of reactive oxygen species (ROS) can cause stress in fungi resulting in growth inhibition. Both eukaryotic and prokaryotic cells have developed numerous mechanisms to counteract and survive the stress in the presence of ROS. In many fungi, the HOG signaling pathway is crucial for the oxidative stress response as well as for osmotic stress response. This study revealed that while the osmotic stress response is only slightly affected by the master regulator veA, this gene, also known to control morphological development and secondary metabolism in numerous fungal species, has a profound effect on the oxidative stress response in the aflatoxin-producing fung

SUBMITTER: Baidya S 

PROVIDER: S-EPMC4135802 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature