Palladium-catalyzed regioselective arylation of 1,1,3-triaryl-2-azaallyl anions with aryl chlorides.

ABSTRACT: A regioselective arylation of 1,1,3-triaryl-2-azaallyl anions with aryl chlorides is described. The palladium-NIXANTPHOS-based catalyst affords diarylmethylamine derivatives in good yield and without product isomerization. A gram scale sequential one-pot ketimine synthesis/arylation protocol was also developed.

SUBMITTER: Li M 

PROVIDER: S-EPMC4136662 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature