Human hair shaft proteomic profiling: individual differences, site specificity and cuticle analysis.

ABSTRACT: Hair from different individuals can be distinguished by physical properties. Although some data exist on other species, examination of the individual molecular differences within the human hair shaft has not been thoroughly investigated. Shotgun proteomic analysis revealed considerable variation in profile among samples from Caucasian, African-American, Kenyan and Korean subjects. Within these ethnic groups, prominent keratin proteins served to distinguish individual profiles. Differences between ethnic groups, less marked, relied to a large extent on levels of keratin associated proteins. In samples from Caucasian subjects, hair shafts from axillary, beard, pubic and scalp regions exhibited distinguishable profiles, with the last being most different from the others. Finally, the profile

SUBMITTER: Laatsch CN 

PROVIDER: S-EPMC4137660 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature