Comparison of contact lens and intraocular lens correction of monocular aphakia during infancy: a randomized clinical trial of HOTV optotype acuity at age 4.5 years and clinical findings at age 5 years.

ABSTRACT:

Importance

The efficacy and safety of primary intraocular lens (IOL) implantation during early infancy is unknown.

Objective

To compare the visual outcomes of patients optically corrected with contact lenses vs IOLs following unilateral cataract surgery during early infancy.

Design, setting, and participants

The Infant Aphakia Treatment Study is a randomized clinical trial with 5 years of follow-up that involved 114 infants with unilateral congenital cataracts at 12 sites. A traveling examiner assessed visual acuity at age 4.5 years.

Interventions

Cataract surgery with or without primary IOL implantation. Contact lenses were used to correct aphakia in patients who did not receive IOLs. Treatment was determined through random assignment.

Main outcomes and mea

SUBMITTER: Infant Aphakia Treatment Study Group 

PROVIDER: S-EPMC4138810 | biostudies-literature | 2014 Jun

REPOSITORIES: biostudies-literature