Secular trends in echocardiographic left ventricular mass in the community: the Framingham Heart Study.

ABSTRACT:

Objective

To investigate secular trends in echocardiographically determined left ventricular mass (LVM).

Design, setting and participants

Longitudinal community-based cohort study in Framingham, Massachussetts. LVM was calculated from routine echocardiography in 4320 participants (52% women) of the Framingham offspring cohort at examination cycles 4 (1987-1991), 5 (1991-1995), 6 (1995-1998) and 8 (2005-2008), totalling 13 971 person-observations.

Main outcome measures

Sex-specific trends in mean LVM (and its components, LV diastolic diameter (LVDD) and LV wall thickness (LVWT)), and LVM indexed to body surface area (BSA).

Results

In men, age-adjusted LVM modestly increased from examination 4 to 8 (192 g to 198 g, p-trend=0.0005), whereas, in women it decreased

SUBMITTER: Kaess BM 

PROVIDER: S-EPMC4139052 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature