Community engagement in diverse populations for Alzheimer disease prevention trials.

ABSTRACT: The recruitment of asymptomatic volunteers has been identified as a critical factor that is delaying the development and validation of preventive therapies for Alzheimer disease (AD). Typical recruitment strategies involve the use of convenience samples or soliciting participation of older adults with a family history of AD from clinics and outreach efforts. However, high-risk groups, such as ethnic/racial minorities, are traditionally less likely to be recruited for AD prevention studies, thus limiting the ability to generalize findings for a significant proportion of the aging population. A community-engagement approach was used to create a registry of 2311 research-ready, healthy adult volunteers who reflect the ethnically diverse local community. Furthermore, the registry's actual comm

SUBMITTER: Romero HR 

PROVIDER: S-EPMC4139415 | biostudies-literature | 2014 Jul-Sep

REPOSITORIES: biostudies-literature