Social relationships and risk of incident mild cognitive impairment in U.S. Alzheimer's disease centers.

ABSTRACT: Social relationships are hypothesized to prevent or slow cognitive decline. We sought to evaluate associations between social relationships and mild cognitive impairment (MCI). Participants from the National Alzheimer's Coordinating Center database who were cognitively normal, aged 55 and older at baseline, and had at least 2 in-person visits (n=5335) were included. Multivariable Cox proportional hazard models evaluated the association between 4 social relationships at baseline (marital status, living situation, having children, and having siblings) and risk of developing MCI (on the basis of clinician diagnosis following established criteria). Primary models were adjusted for baseline demographics. Participants were followed, on average, for 3.2 years; 15.2% were diagnosed with MCI. Compa

SUBMITTER: Brenowitz WD 

PROVIDER: S-EPMC4139444 | biostudies-literature | 2014 Jul-Sep

REPOSITORIES: biostudies-literature