Third-wave cognitive therapy versus mentalisation-based treatment for major depressive disorder: a randomised clinical trial.

ABSTRACT:

Objective

To compare the benefits and harms of third-wave cognitive therapy versus mentalisation-based therapy in a small sample of depressed participants.

Setting

The trial was conducted at an outpatient psychiatric clinic for non-psychotic patients in Roskilde, Denmark.

Participants

44 consecutive adult participants diagnosed with major depressive disorder.

Interventions

18 weeks of third-wave cognitive therapy (n=22) versus 18 weeks of mentalisation-based treatment (n=22).

Outcomes

The primary outcome was the Hamilton Rating Scale for Depression (HDRS) at end of treatment (18 weeks). Secondary outcomes were: remission (HDRS <8), Beck's Depression Inventory, Symptom Checklist 90 Revised and The WHO-Five Well-being Index 1999.

Results

The trial i

SUBMITTER: Jakobsen JC 

PROVIDER: S-EPMC4139625 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature