Adherence to dual antiplatelet therapy after coronary stenting: a systematic review.

ABSTRACT:

Background

Adherence to dual antiplatelet therapy (DAPT) is critical after coronary stenting. Although adherence rates are frequently assessed in clinical trials, adherence rates in the unselected population recommended for treatment but beyond clinical trials are largely unknown. Therefore, we performed a systematic review of published observational studies to describe rates of DAPT adherence, trends in DAPT use over time, and patient-level factors associated with nonadherence.

Hypothesis

DAPT adherence declines with increasing time after drug-eluting stent implantation.

Methods

PubMed, Cumulative Index to Nursing and Allied Health Literature, Embase, and Web of Knowledge were searched through November 20, 2012 for studies including patients receiving 1 or more drug-

SUBMITTER: Czarny MJ 

PROVIDER: S-EPMC4140973 | biostudies-literature | 2014 Aug

REPOSITORIES: biostudies-literature