Ontology highlight
ABSTRACT:
SUBMITTER: Guan Z
PROVIDER: S-EPMC4141794 | biostudies-literature | 2014
REPOSITORIES: biostudies-literature
PloS one 20140822 8
A crude extract of earthworms was used as an eco-friendly, environmentally benign, and easily accessible biocatalyst for various organic synthesis including the asymmetric direct aldol and Mannich reactions, Henry and Biginelli reactions, direct three-component aza-Diels-Alder reactions for the synthesis of isoquinuclidines, and domino reactions for the synthesis of coumarins. Most of these reactions have never before seen in nature, and moderate to good enantioselectivities in aldol and Mannich ...[more]