Functional connectivity during cognitive control in children with autism spectrum disorder: an independent component analysis.

ABSTRACT: Restrictive and repetitive behavior in autism may be related to deficits in cognitive control. Here, we aimed to assess functional connectivity during a cognitive control task and compare brain network activity and connectivity in children with autism spectrum disorders (ASD) and typically developing children using a multivariate data-driven approach. 19 high-functioning boys with ASD and 19 age-matched typically developing boys were included in this study. Functional magnetic resonance imaging was performed at 3T during the performance of a cognitive control task (go/no-go paradigm). Functional networks were identified using independent component analysis. Network activity and connectivity was compared between groups and correlated with clinical measures of rigid behavior using multivaria

SUBMITTER: Ambrosino S 

PROVIDER: S-EPMC4141973 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature