Periaortic fat and cardiovascular risk: a comparison of high-risk older adults and age-matched healthy controls.

ABSTRACT:

Objective

Fat accumulation around the heart and aorta may impact cardiovascular (CV) health. The purpose of this study was to conduct a systematic investigation to examine potential associations of these fat depots with risk factors for CV events, which has not been done before.

Methods

Pericardial fat, periaortic fat around the ascending aorta (AA), descending aorta (DA) and aortic arch, and abdominal subcutaneous and visceral fat were measured by MRI in older adults with (n = 385, 69 ± 8 years, 52% female) and without (n = 50, 69 ± 8 years, 58% female) risk factors for a CV event.

Results

Individuals with CV risk factors exhibited greater fat volumes across all fat depots compared with those without risk factors. In analysis of covariance accounting for age, gender,

SUBMITTER: Brinkley TE 

PROVIDER: S-EPMC4143481 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature