Glycemic index, glycemic load, and risk of type 2 diabetes: results from 3 large US cohorts and an updated meta-analysis.

ABSTRACT:

Background

Epidemiologic evidence for the relation between carbohydrate quality and risk of type 2 diabetes (T2D) has been mixed.

Objective

We prospectively examined the association of dietary glycemic index (GI) and glycemic load (GL) with T2D risk.

Design

We prospectively followed 74,248 women from the Nurses' Health Study (1984-2008), 90,411 women from the Nurses' Health Study II (1991-2009), and 40,498 men from the Health Professionals Follow-Up Study (1986-2008) who were free of diabetes, cardiovascular disease, and cancer at baseline. Diet was assessed by using a validated questionnaire and updated every 4 y. We also conducted an updated meta-analysis, including results from our 3 cohorts and other studies.

Results

During 3,800,618 person-years of follow-

SUBMITTER: Bhupathiraju SN 

PROVIDER: S-EPMC4144100 | biostudies-literature | 2014 Jul

REPOSITORIES: biostudies-literature