Medical status of 219 children with biliary atresia surviving long-term with their native livers: results from a North American multicenter consortium.

ABSTRACT:

Objectives

To examine the medical status of children with biliary atresia (BA) with their native livers after hepato- portoenterostomy (HPE) surgery.

Study design

The Childhood Liver Disease Research and Education Network database was utilized to examine subjects with BA living with their native livers 5 or more years after HPE and to describe the prevalence of subjects with BA with an "ideal" outcome, defined as no clinical evidence of chronic liver disease, normal liver biochemical indices (aspartate aminotransferase, alanine aminotransferase, γ-glutamyl transpeptidase, platelet count, total bilirubin, international normalized ratio, and albumin), and normal health-related quality of life 5 or more years after HPE.

Results

Children with BA (n = 219; 43% male) with m

SUBMITTER: Ng VL 

PROVIDER: S-EPMC4144331 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature