Association of systolic blood pressure levels with cardiovascular events and all-cause mortality among older adults taking antihypertensive medication.

ABSTRACT:

Introduction

The aim of the study was to identify the association of systolic blood pressure (SBP) levels with cardiovascular events, all-cause mortality, and falls among elderly persons taking antihypertensive medication.

Methods

US adults ≥ 45 years of age taking antihypertensive medication enrolled in the REGARDS study were categorized into 3 age groups: 55-64, 65-74 and ≥ 75 years old and baseline on-treatment SBP levels. Our primary analyses focused on incident cardiovascular disease (CVD) (n=9787) and all-cause mortality (n=13,948).

Results

During follow-up, 530 (5.4%) participants had CVD events and 2095 (15%) participants died. After multivariable adjustment among participants ≥ 75, the incidence of CVD per 1000 person-years (95% confidence interval) was 16.9

SUBMITTER: Banach M 

PROVIDER: S-EPMC4144437 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature