Allelic variant in the anti-Mullerian hormone gene leads to autosomal and temperature-dependent sex reversal in a selected Nile tilapia line.

ABSTRACT: Owing to the demand for sustainable sex-control protocols in aquaculture, research in tilapia sex determination is gaining momentum. The mutual influence of environmental and genetic factors hampers disentangling the complex sex determination mechanism in Nile tilapia (Oreochromis niloticus). Previous linkage analyses have demonstrated quantitative trait loci for the phenotypic sex on linkage groups 1, 3, and 23. Quantitative trait loci for temperature-dependent sex reversal similarly reside on linkage group 23. The anti-Müllerian hormone gene (amh), located in this genomic region, is important for sexual fate in higher vertebrates, and shows sexually dimorphic expression in Nile tilapia. Therefore this study aimed at detecting allelic variants and marker-sex associations in the amh gene.

SUBMITTER: Wessels S 

PROVIDER: S-EPMC4144872 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature